Decoupling Activation of Heme Biosynthesis from Anaerobic Toxicity in a Molecule Active in Staphylococcus aureus.

Dutter BF, Mike LA, Reid PR, Chong KM, Ramos-Hunter SJ, Skaar EP, Sulikowski GA
ACS Chem Biol. 2016 11 (5): 1354-61

PMID: 26890615 · PMCID: PMC5117894 · DOI:10.1021/acschembio.5b00934

MeSH Terms (11)

Anti-Bacterial Agents Bacteria, Anaerobic Heme Humans Iron Oxygen Pyrazoles Small Molecule Libraries Staphylococcal Infections Staphylococcus aureus Structure-Activity Relationship

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