Endogenous dendritic cells from the tumor microenvironment support T-ALL growth via IGF1R activation.

Triplett TA, Cardenas KT, Lancaster JN, Hu Z, Selden HJ, Jasso GJ, Balasubramanyam S, Chan K, Li L, Chen X, Marcogliese AN, Davé UP, Love PE, Ehrlich LI
Proc Natl Acad Sci U S A. 2016 113 (8): E1016-25

PMID: 26862168 · PMCID: PMC4776467 · DOI:10.1073/pnas.1520245113

MeSH Terms (15)

Animals Cell Line, Tumor Cell Survival Dendritic Cells Female Humans Male Mice Neoplasm Proteins Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Receptor, IGF Type 1 Receptor, Platelet-Derived Growth Factor beta Receptors, Somatomedin Signal Transduction Tumor Microenvironment

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