A G Protein-biased Designer G Protein-coupled Receptor Useful for Studying the Physiological Relevance of Gq/11-dependent Signaling Pathways.

Hu J, Stern M, Gimenez LE, Wanka L, Zhu L, Rossi M, Meister J, Inoue A, Beck-Sickinger AG, Gurevich VV, Wess J
J Biol Chem. 2016 291 (15): 7809-20

PMID: 26851281 · PMCID: PMC4824988 · DOI:10.1074/jbc.M115.702282

MeSH Terms (18)

Animals Arrestins beta-Arrestins Calcium Cells, Cultured Chlorocebus aethiops COS Cells Gene Knockdown Techniques Glucose GTP-Binding Protein alpha Subunits, Gq-G11 HEK293 Cells Hepatocytes Humans Mice, Inbred C57BL Protein Interaction Mapping Protein Interaction Maps Receptors, G-Protein-Coupled Signal Transduction

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