Active medulloblastoma enhancers reveal subgroup-specific cellular origins.

Lin CY, Erkek S, Tong Y, Yin L, Federation AJ, Zapatka M, Haldipur P, Kawauchi D, Risch T, Warnatz HJ, Worst BC, Ju B, Orr BA, Zeid R, Polaski DR, Segura-Wang M, Waszak SM, Jones DT, Kool M, Hovestadt V, Buchhalter I, Sieber L, Johann P, Chavez L, Gröschel S, Ryzhova M, Korshunov A, Chen W, Chizhikov VV, Millen KJ, Amstislavskiy V, Lehrach H, Yaspo ML, Eils R, Lichter P, Korbel JO, Pfister SM, Bradner JE, Northcott PA
Nature. 2016 530 (7588): 57-62

PMID: 26814967 · PMCID: PMC5168934 · DOI:10.1038/nature16546

MeSH Terms (15)

Animals Cerebellar Neoplasms Enhancer Elements, Genetic Female Gene Expression Regulation, Neoplastic Gene Regulatory Networks Genes, Neoplasm Genes, Reporter Humans Male Medulloblastoma Mice Reproducibility of Results Transcription Factors Zebrafish

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