Cloning and structure of a yeast gene encoding a general transcription initiation factor TFIID that binds to the TATA box.

Horikoshi M, Wang CK, Fujii H, Cromlish JA, Weil PA, Roeder RG
Nature. 1989 341 (6240): 299-303

PMID: 2677740 · DOI:10.1038/341299a0

The TATA sequence-binding factor TFIID plays a central role both in promoter activation by RNA polymerase II and other common initiation factors, and in promoter regulation by gene-specific factors. The sequence of yeast TFIID, which seems to be encoded by a single gene, contains interesting structural motifs that are possibly involved in these functions, and is similar to sequences of bacterial sigma factors.

MeSH Terms (17)

Amino Acid Sequence Base Sequence Chromosomes, Fungal Cloning, Molecular DNA, Fungal Gene Expression Genes Genes, Fungal Molecular Sequence Data Promoter Regions, Genetic Protein Binding RNA, Messenger Saccharomyces cerevisiae Sequence Homology, Nucleic Acid Transcription, Genetic Transcription Factors Transcription Factor TFIID

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