Analysis of TcdB Proteins within the Hypervirulent Clade 2 Reveals an Impact of RhoA Glucosylation on Clostridium difficile Proinflammatory Activities.

Quesada-Gómez C, López-Ureña D, Chumbler N, Kroh HK, Castro-Peña C, Rodríguez C, Orozco-Aguilar J, González-Camacho S, Rucavado A, Guzmán-Verri C, Lawley TD, Lacy DB, Chaves-Olarte E
Infect Immun. 2016 84 (3): 856-65

PMID: 26755157 · PMCID: PMC4771349 · DOI:10.1128/IAI.01291-15

MeSH Terms (13)

Animals Bacterial Proteins Bacterial Toxins Clostridioides difficile Enterocolitis, Pseudomembranous Genotype Glycosylation Host-Pathogen Interactions Humans Male Mice rhoA GTP-Binding Protein Virulence

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