Hydrolytic charge-reversal of PEGylated polyplexes enhances intracellular un-packaging and activity of siRNA.

Werfel TA, Swain C, Nelson CE, Kilchrist KV, Evans BC, Miteva M, Duvall CL
J Biomed Mater Res A. 2016 104 (4): 917-27

PMID: 26691570 · PMCID: PMC5517028 · DOI:10.1002/jbm.a.35629

MeSH Terms (14)

Amines Carboxylic Acids Cell Line, Tumor Cell Survival Fluorescence Resonance Energy Transfer Hemolysis Humans Hydrolysis Methacrylates Microscopy, Confocal Nanostructures Polyethylene Glycols RNA, Small Interfering RNA Interference

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