Treatment of Triple-Negative Breast Cancer with TORC1/2 Inhibitors Sustains a Drug-Resistant and Notch-Dependent Cancer Stem Cell Population.

Bhola NE, Jansen VM, Koch JP, Li H, Formisano L, Williams JA, Grandis JR, Arteaga CL
Cancer Res. 2016 76 (2): 440-52

PMID: 26676751 · PMCID: PMC4715956 · DOI:10.1158/0008-5472.CAN-15-1640-T

MeSH Terms (10)

Cell Line, Tumor Drug Resistance, Neoplasm Humans Mechanistic Target of Rapamycin Complex 2 Multiprotein Complexes Neoplastic Stem Cells Signal Transduction TOR Serine-Threonine Kinases Triple Negative Breast Neoplasms Xenograft Model Antitumor Assays

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