CYP2C19 and CES1 polymorphisms and efficacy of clopidogrel and aspirin dual antiplatelet therapy in patients with symptomatic intracranial atherosclerotic disease.

Hoh BL, Gong Y, McDonough CW, Waters MF, Royster AJ, Sheehan TO, Burkley B, Langaee TY, Mocco J, Zuckerman SL, Mummareddy N, Stephens ML, Ingram C, Shaffer CM, Denny JC, Brilliant MH, Kitchner TE, Linneman JG, Roden DM, Johnson JA
J Neurosurg. 2016 124 (6): 1746-51

PMID: 26587656 · PMCID: PMC4915569 · DOI:10.3171/2015.6.JNS15795

MeSH Terms (20)

Aged Aspirin Carboxylic Ester Hydrolases Clopidogrel Cytochrome P-450 CYP2C19 Female Gene Frequency Genotyping Techniques Heterozygote Humans Intracranial Arteriosclerosis Ischemic Attack, Transient Kaplan-Meier Estimate Male Myocardial Infarction Platelet Aggregation Inhibitors Polymorphism, Single Nucleotide Prospective Studies Stroke Ticlopidine

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