Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress.

Fox JM, Long F, Edeling MA, Lin H, van Duijl-Richter MKS, Fong RH, Kahle KM, Smit JM, Jin J, Simmons G, Doranz BJ, Crowe JE, Fremont DH, Rossmann MG, Diamond MS
Cell. 2015 163 (5): 1095-1107

PMID: 26553503 · PMCID: PMC4659373 · DOI:10.1016/j.cell.2015.10.050

MeSH Terms (21)

Alphavirus Alphavirus Infections Amino Acid Sequence Animals Antibodies, Monoclonal Antibodies, Neutralizing Antibodies, Viral Chikungunya virus Cryoelectron Microscopy Epitopes Glycoproteins Humans Immunoglobulin Fab Fragments Mice Models, Molecular Molecular Sequence Data Protein Structure, Tertiary Sequence Alignment Viral Envelope Proteins Viral Vaccines Virus Internalization

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