The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions.

Mullins EA, Shi R, Parsons ZD, Yuen PK, David SS, Igarashi Y, Eichman BF
Nature. 2015 527 (7577): 254-8

PMID: 26524531 · PMCID: PMC4896645 · DOI:10.1038/nature15728

MeSH Terms (13)

Bacillus cereus Base Pairing Biocatalysis Catalytic Domain Crystallography, X-Ray DNA Adducts DNA Damage DNA Glycosylases DNA Repair Duocarmycins Indoles Models, Molecular Pyrroles

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