Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids.

Freedman BS, Brooks CR, Lam AQ, Fu H, Morizane R, Agrawal V, Saad AF, Li MK, Hughes MR, Werff RV, Peters DT, Lu J, Baccei A, Siedlecki AM, Valerius MT, Musunuru K, McNagny KM, Steinman TI, Zhou J, Lerou PH, Bonventre JV
Nat Commun. 2015 6: 8715

PMID: 26493500 · PMCID: PMC4620584 · DOI:10.1038/ncomms9715

MeSH Terms (12)

Cell Differentiation Clustered Regularly Interspaced Short Palindromic Repeats Embryonic Stem Cells Gene Knockout Techniques Germ Layers Humans Kidney Kidney Diseases Models, Biological Organoids Pluripotent Stem Cells Sialoglycoproteins

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