Outer surface protein OspC is an antiphagocytic factor that protects Borrelia burgdorferi from phagocytosis by macrophages.

Carrasco SE, Troxell B, Yang Y, Brandt SL, Li H, Sandusky GE, Condon KW, Serezani CH, Yang XF
Infect Immun. 2015 83 (12): 4848-60

PMID: 26438793 · PMCID: PMC4645385 · DOI:10.1128/IAI.01215-15

MeSH Terms (21)

Animals Antigens, Bacterial B-Lymphocytes Bacterial Outer Membrane Proteins Borrelia burgdorferi Cell Line Female Gene Expression Regulation, Bacterial Genes, Reporter Green Fluorescent Proteins Humans Immune Evasion Killer Cells, Natural Lyme Disease Macrophages, Peritoneal Mice Mice, Inbred NOD Mice, Knockout Mice, SCID Neutrophils T-Lymphocytes

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