RePORT International: Advancing Tuberculosis Biomarker Research Through Global Collaboration.

Hamilton CD, Swaminathan S, Christopher DJ, Ellner J, Gupta A, Sterling TR, Rolla V, Srinivasan S, Karyana M, Siddiqui S, Stoszek SK, Kim P
Clin Infect Dis. 2015 61Suppl 3: S155-9

PMID: 26409277 · PMCID: PMC4583572 · DOI:10.1093/cid/civ611

Progress in tuberculosis clinical research is hampered by a lack of reliable biomarkers that predict progression from latent to active tuberculosis, and subsequent cure, relapse, or failure. Regional Prospective Observational Research in Tuberculosis (RePORT) International represents a consortium of regional cohorts (RePORT India, RePORT Brazil, and RePORT Indonesia) that are linked through the implementation of a Common Protocol for data and specimen collection, and are poised to address this critical research need. Each RePORT network is designed to support local, in-country tuberculosis-specific data and specimen biorepositories, and associated research. Taken together, the expected results include greater global clinical research capacity in high-burden settings, and increased local access to quality data and specimens for members of each network and their domestic and international collaborators. Additional networks are expected to be added, helping to spur tuberculosis treatment and prevention research around the world.

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MeSH Terms (11)

Biological Specimen Banks Biomarkers Biomedical Research Brazil Humans India Indonesia International Cooperation Prospective Studies Specimen Handling Tuberculosis

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