Bilirubin prevents acute DSS-induced colitis by inhibiting leukocyte infiltration and suppressing upregulation of inducible nitric oxide synthase.

Zucker SD, Vogel ME, Kindel TL, Smith DL, Idelman G, Avissar U, Kakarlapudi G, Masnovi ME
Am J Physiol Gastrointest Liver Physiol. 2015 309 (10): G841-54

PMID: 26381705 · PMCID: PMC4652140 · DOI:10.1152/ajpgi.00149.2014

MeSH Terms (17)

Animals Bilirubin Cell Movement Colitis Colon Cytotoxins Dextran Sulfate Interleukin-5 Intestinal Mucosa Leukocytes Male Mice Mice, Inbred C57BL Nitric Oxide Synthase Type II Protective Agents Up-Regulation Vascular Cell Adhesion Molecule-1

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