Partial mGlu₅ Negative Allosteric Modulators Attenuate Cocaine-Mediated Behaviors and Lack Psychotomimetic-Like Effects.

Gould RW, Amato RJ, Bubser M, Joffe ME, Nedelcovych MT, Thompson AD, Nickols HH, Yuh JP, Zhan X, Felts AS, Rodriguez AL, Morrison RD, Byers FW, Rook JM, Daniels JS, Niswender CM, Conn PJ, Emmitte KA, Lindsley CW, Jones CK
Neuropsychopharmacology. 2016 41 (4): 1166-78

PMID: 26315507 · PMCID: PMC4748441 · DOI:10.1038/npp.2015.265

MeSH Terms (20)

Alkynes Allosteric Regulation Animals Anti-Anxiety Agents Antidepressive Agents Brain Cocaine Conditioning, Classical Conditioning, Operant Dose-Response Relationship, Drug Drug-Seeking Behavior Male Mice Motor Activity Phencyclidine Pyridines Rats, Sprague-Dawley Receptor, Metabotropic Glutamate 5 Self Administration Thiazoles

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