Publication

Signal Transducer and Activator of Transcription 3, Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer.

Nagathihalli NS, Castellanos JA, Shi C, Beesetty Y, Reyzer ML, Caprioli R, Chen X, Walsh AJ, Skala MC, Moses HL, Merchant NB
Gastroenterology. 2015 149 (7): 1932-1943.e9

PMID: 26255562 · PMCID: PMC4863449 · DOI:10.1053/j.gastro.2015.07.058

MeSH Terms (33)

Animals Antineoplastic Combined Chemotherapy Protocols Carcinoma, Pancreatic Ductal Cell Line, Tumor Collagen Deoxycytidine Drug Resistance, Neoplasm Gene Knockdown Techniques Humans Mice, Inbred C57BL Mice, Nude Mice, Transgenic Molecular Targeted Therapy Neoplasm Staging Osteonectin Pancreatic Neoplasms Phosphorylation Protein-Serine-Threonine Kinases Proto-Oncogene Proteins p21(ras) Pyrazoles Pyrimidines Receptor, Transforming Growth Factor-beta Type II Receptors, Transforming Growth Factor beta Signal Transduction Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization STAT3 Transcription Factor Stromal Cells Time Factors Transcription Factors Transfection Tumor Burden Tumor Microenvironment Xenograft Model Antitumor Assays

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