Report from the National Institute of Allergy and Infectious Diseases workshop on drug allergy.

Wheatley LM, Plaut M, Schwaninger JM, Banerji A, Castells M, Finkelman FD, Gleich GJ, Guttman-Yassky E, Mallal SA, Naisbitt DJ, Ostrov DA, Phillips EJ, Pichler WJ, Platts-Mills TA, Roujeau JC, Schwartz LB, Trepanier LA
J Allergy Clin Immunol. 2015 136 (2): 262-71.e2

PMID: 26254053 · PMCID: PMC4529958 · DOI:10.1016/j.jaci.2015.05.027

Allergic reactions to drugs are a serious public health concern. In 2013, the Division of Allergy, Immunology, and Transplantation of the National Institute of Allergy and Infectious Diseases sponsored a workshop on drug allergy. International experts in the field of drug allergy with backgrounds in allergy, immunology, infectious diseases, dermatology, clinical pharmacology, and pharmacogenomics discussed the current state of drug allergy research. These experts were joined by representatives from several National Institutes of Health institutes and the US Food and Drug Administration. The participants identified important advances that make new research directions feasible and made suggestions for research priorities and for development of infrastructure to advance our knowledge of the mechanisms, diagnosis, management, and prevention of drug allergy. The workshop summary and recommendations are presented herein.

Published by Elsevier Inc.

MeSH Terms (16)

Carbamazepine Dideoxynucleosides Drug Hypersensitivity Gene Expression Haptens HLA Antigens Humans Immunoglobulin E National Institute of Allergy and Infectious Diseases (U.S.) Practice Guidelines as Topic Receptors, Antigen, T-Cell Stevens-Johnson Syndrome Terminology as Topic Translational Medical Research United States Virus Diseases

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