DNA polymerases κ and ζ cooperatively perform mutagenic translesion synthesis of the C8-2'-deoxyguanosine adduct of the dietary mutagen IQ in human cells.

Bose A, Pande P, Jasti VP, Millsap AD, Hawkins EK, Rizzo CJ, Basu AK
Nucleic Acids Res. 2015 43 (17): 8340-51

PMID: 26220181 · PMCID: PMC4787813 · DOI:10.1093/nar/gkv750

MeSH Terms (9)

Deoxyguanosine DNA DNA-Directed DNA Polymerase DNA Adducts HEK293 Cells Humans Mutagens Mutation Rate Quinolines

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