Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing.

Chiou SH, Winters IP, Wang J, Naranjo S, Dudgeon C, Tamburini FB, Brady JJ, Yang D, GrĂ¼ner BM, Chuang CH, Caswell DR, Zeng H, Chu P, Kim GE, Carpizo DR, Kim SK, Winslow MM
Genes Dev. 2015 29 (14): 1576-85

PMID: 26178787 · PMCID: PMC4526740 · DOI:10.1101/gad.264861.115

MeSH Terms (13)

Adenocarcinoma Animals Carcinoma, Pancreatic Ductal Clustered Regularly Interspaced Short Palindromic Repeats Disease Models, Animal Gene Expression Regulation, Neoplastic Genetic Vectors Genome Humans Lentivirus Mice Mice, Inbred C57BL Mice, Transgenic

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