Isolation and Characterization of Broad and Ultrapotent Human Monoclonal Antibodies with Therapeutic Activity against Chikungunya Virus.

Smith SA, Silva LA, Fox JM, Flyak AI, Kose N, Sapparapu G, Khomandiak S, Khomadiak S, Ashbrook AW, Kahle KM, Fong RH, Swayne S, Doranz BJ, McGee CE, Heise MT, Pal P, Brien JD, Austin SK, Diamond MS, Dermody TS, Crowe JE
Cell Host Microbe. 2015 18 (1): 86-95

PMID: 26159721 · PMCID: PMC4501771 · DOI:10.1016/j.chom.2015.06.009

MeSH Terms (17)

Animals Antibodies, Monoclonal Antibodies, Neutralizing Antibodies, Viral Chemoprevention Chikungunya Fever Chikungunya virus Disease Models, Animal Humans Immunization, Passive Inhibitory Concentration 50 Mice Protein Binding Survival Analysis Treatment Outcome Viral Envelope Proteins Virus Internalization

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