Design of Protein Multi-specificity Using an Independent Sequence Search Reduces the Barrier to Low Energy Sequences.

Sevy AM, Jacobs TM, Crowe JE, Meiler J
PLoS Comput Biol. 2015 11 (7): e1004300

PMID: 26147100 · PMCID: PMC4493036 · DOI:10.1371/journal.pcbi.1004300

MeSH Terms (16)

Algorithms Amino Acid Sequence Binding Sites Computer Simulation Directed Molecular Evolution Drug Design Energy Transfer Models, Chemical Models, Molecular Molecular Sequence Data Protein Binding Protein Engineering Proteins Sequence Analysis, Protein Structure-Activity Relationship Thermodynamics

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