TRAIL-Based High Throughput Screening Reveals a Link between TRAIL-Mediated Apoptosis and Glutathione Reductase, a Key Component of Oxidative Stress Response.

Rozanov D, Cheltsov A, Sergienko E, Vasile S, Golubkov V, Aleshin AE, Levin T, Traer E, Hann B, Freimuth J, Alexeev N, Alekseyev MA, Budko SP, B├Ąchinger HP, Spellman P
PLoS One. 2015 10 (6): e0129566

PMID: 26075913 · PMCID: PMC4468210 · DOI:10.1371/journal.pone.0129566

MeSH Terms (16)

Animals Antineoplastic Agents Apoptosis Cell Line, Tumor Dose-Response Relationship, Drug Doxorubicin Drug Discovery Glutathione Glutathione Reductase High-Throughput Screening Assays Humans Mice Oxidative Stress Reactive Oxygen Species Small Molecule Libraries TNF-Related Apoptosis-Inducing Ligand

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