Iron Toxicity in the Retina Requires Alu RNA and the NLRP3 Inflammasome.

Gelfand BD, Wright CB, Kim Y, Yasuma T, Yasuma R, Li S, Fowler BJ, Bastos-Carvalho A, Kerur N, Uittenbogaard A, Han YS, Lou D, Kleinman ME, McDonald WH, Núñez G, Georgel P, Dunaief JL, Ambati J
Cell Rep. 2015 11 (11): 1686-93

PMID: 26074074 · PMCID: PMC4481133 · DOI:10.1016/j.celrep.2015.05.023

MeSH Terms (13)

Alu Elements Animals Carrier Proteins Caspase 1 DEAD-box RNA Helicases Inflammasomes Iron Mice Mice, Inbred C57BL NLR Family, Pyrin Domain-Containing 3 Protein Retinal Pigment Epithelium Ribonuclease III RNA-Binding Proteins

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