Macrophage SR-BI mediates efferocytosis via Src/PI3K/Rac1 signaling and reduces atherosclerotic lesion necrosis.

Tao H, Yancey PG, Babaev VR, Blakemore JL, Zhang Y, Ding L, Fazio S, Linton MF
J Lipid Res. 2015 56 (8): 1449-60

PMID: 26059978 · PMCID: PMC4513986 · DOI:10.1194/jlr.M056689

MeSH Terms (20)

Animals Apoptosis Atherosclerosis CD36 Antigens Cell Survival Collagen Gene Deletion Hematopoiesis Macrophages Mice Mice, Inbred C57BL Necrosis Phagocytosis Phagosomes Phosphatidylinositol 3-Kinases Phosphatidylserines Protein Transport rac1 GTP-Binding Protein Signal Transduction src-Family Kinases

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