A Murine Model of K-RAS and β-Catenin Induced Renal Tumors Expresses High Levels of E2F1 and Resembles Human Wilms Tumor.

Yi Y, Polosukhina D, Love HD, Hembd A, Pickup M, Moses HL, Lovvorn HN, Zent R, Clark PE
J Urol. 2015 194 (6): 1762-70

PMID: 25934441 · PMCID: PMC4782590 · DOI:10.1016/j.juro.2015.04.090

MeSH Terms (17)

Animals beta Catenin Disease Models, Animal E2F1 Transcription Factor Gene Expression Regulation, Neoplastic Genotype Kidney Kidney Neoplasms Mice Mice, Mutant Strains Oligonucleotide Array Sequence Analysis Proto-Oncogene Proteins p21(ras) Transcriptional Activation Transcriptome Tumor Suppressor Protein p53 Up-Regulation Wilms Tumor

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