The catalytic domains of Clostridium sordellii lethal toxin and related large clostridial glucosylating toxins specifically recognize the negatively charged phospholipids phosphatidylserine and phosphatidic acid.

Varela Chavez C, Hoos S, Haustant GM, Chenal A, England P, Blondel A, Pauillac S, Lacy DB, Popoff MR
Cell Microbiol. 2015 17 (10): 1477-93

PMID: 25882477 · DOI:10.1111/cmi.12449

MeSH Terms (10)

Anions Bacterial Toxins Binding Sites Catalytic Domain Cell Membrane Enzyme-Linked Immunosorbent Assay Phosphatidic Acids Phosphatidylserines Protein Binding Surface Plasmon Resonance

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