Human Cytochrome P450 21A2, the Major Steroid 21-Hydroxylase: STRUCTURE OF THE ENZYME┬ĚPROGESTERONE SUBSTRATE COMPLEX AND RATE-LIMITING C-H BOND CLEAVAGE.

Pallan PS, Wang C, Lei L, Yoshimoto FK, Auchus RJ, Waterman MR, Guengerich FP, Egli M
J Biol Chem. 2015 290 (21): 13128-43

PMID: 25855791 · PMCID: PMC4505568 · DOI:10.1074/jbc.M115.646307

MeSH Terms (19)

Amino Acid Sequence Animals Binding Sites Catalysis Catalytic Domain Cattle Crystallography, X-Ray Deuterium Humans Hydroxylation Kinetics Molecular Sequence Data Oxidation-Reduction Progesterone Protein Binding Protein Conformation Sequence Homology, Amino Acid Steroid 21-Hydroxylase Substrate Specificity

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