Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC.

Thomas LR, Wang Q, Grieb BC, Phan J, Foshage AM, Sun Q, Olejniczak ET, Clark T, Dey S, Lorey S, Alicie B, Howard GC, Cawthon B, Ess KC, Eischen CM, Zhao Z, Fesik SW, Tansey WP
Mol Cell. 2015 58 (3): 440-52

PMID: 25818646 · PMCID: PMC4427524 · DOI:10.1016/j.molcel.2015.02.028

MeSH Terms (23)

Amino Acid Motifs Amino Acid Sequence Animals Anisotropy Binding Sites Carcinogenesis Chromatin Fluorescence Polarization HEK293 Cells Humans Intracellular Signaling Peptides and Proteins Mice Mice, Nude Models, Molecular Molecular Sequence Data Mutation NIH 3T3 Cells Protein Binding Proteins Protein Structure, Tertiary Proto-Oncogene Proteins c-myc Sequence Homology, Amino Acid Two-Hybrid System Techniques

Connections (3)

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