Acute Inhibition of MEK Suppresses Congenital Melanocytic Nevus Syndrome in a Murine Model Driven by Activated NRAS and Wnt Signaling.

Pawlikowski JS, Brock C, Chen SC, Al-Olabi L, Nixon C, McGregor F, Paine S, Chanudet E, Lambie W, Holmes WM, Mullin JM, Richmond A, Wu H, Blyth K, King A, Kinsler VA, Adams PD
J Invest Dermatol. 2015 135 (8): 2093-2101

PMID: 25815427 · PMCID: PMC4539947 · DOI:10.1038/jid.2015.114

MeSH Terms (18)

Animals Child Disease Models, Animal DNA Female Humans Male MAP Kinase Kinase Kinases Membrane Proteins Mice Mice, Inbred C57BL Monomeric GTP-Binding Proteins Mutation Nevus, Pigmented Sequence Analysis, DNA Signal Transduction Skin Neoplasms Wnt Proteins

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