Phosphorescence monitoring of hypoxic microenvironment in solid-tumors to evaluate chemotherapeutic effects using the hypoxia-sensitive iridium (III) coordination compound.

Zeng Y, Liu Y, Shang J, Ma J, Wang R, Deng L, Guo Y, Zhong F, Bai M, Zhang S, Wu D
PLoS One. 2015 10 (3): e0121293

PMID: 25786221 · PMCID: PMC4365010 · DOI:10.1371/journal.pone.0121293

MeSH Terms (18)

Adenocarcinoma Animals Antineoplastic Agents Biological Transport Cell Hypoxia Cell Line, Tumor Cell Survival Cisplatin Colonic Neoplasms Coordination Complexes Iridium Luminescent Agents Luminescent Measurements Mice Optical Imaging Organometallic Compounds Treatment Outcome Tumor Microenvironment

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