Site-specific, intramolecular cross-linking of Pin1 active site residues by the lipid electrophile 4-oxo-2-nonenal.

Aluise CD, Camarillo JM, Shimozu Y, Galligan JJ, Rose KL, Tallman KA, Marnett LJ
Chem Res Toxicol. 2015 28 (4): 817-27

PMID: 25739016 · PMCID: PMC4480626 · DOI:10.1021/acs.chemrestox.5b00038

MeSH Terms (9)

Aldehydes Catalytic Domain Cell Line, Tumor Cross-Linking Reagents Humans NIMA-Interacting Peptidylprolyl Isomerase Oxidative Stress Peptidylprolyl Isomerase Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

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