Cohort Profile: The Shanghai Men's Health Study.

Shu XO, Li H, Yang G, Gao J, Cai H, Takata Y, Zheng W, Xiang YB
Int J Epidemiol. 2015 44 (3): 810-8

PMID: 25733578 · PMCID: PMC4521127 · DOI:10.1093/ije/dyv013

The Shanghai Men's Health Study (SMHS) is a population-based cohort study of 61,480 men aged 40-74 years, launched in 2002 in urban Shanghai to investigate the contribution of lifestyle/environmental factors and genetic susceptibility to cancer and other non-communicable diseases (NCDs). At baseline, trained interviewers collected detailed information on personal and dietary habits, occupational/medical history and physical activity, and took anthropometric measurements (response rate: 74%). Blood, urine and DNA were collected from 75%, 89% and 89% of participants, respectively. The cohort has been followed up through a combination of in-person surveys every 3-4 years and annual record linkage with cancer and vital statistics registries. Response rates for in-person follow-up surveys were over 91% and coverage for mortality nearly 100%. SMHS participants have a high smoking rate (58.6%) and moderate alcohol-drinking rate (29.3%), but low obesity rate (2.6%). They have a low calorie intake from fat (16.2% of total calorie intake) and protein (16.4%), high calorie intake from carbohydrates (67.4%), and high intake of soy food, cruciferous vegetables and fish (156.5, 110.6 and 51.7 g/day, respectively). With its unique exposure pattern and wealth of data and biological samples, the SMHS is well positioned for long-term research into NCD aetiology and prognosis. Information about accessing the SMHS resources can be found at:

© The Author 2015; all rights reserved. Published by Oxford University Press on behalf of the International Epidemiological Association.

MeSH Terms (23)

Adult Aged Alcohol Drinking Cause of Death China Cohort Studies Diabetes Mellitus, Type 2 Environment Feeding Behavior Genetic Predisposition to Disease Humans Life Style Male Men's Health Middle Aged Motor Activity Neoplasms Obesity Risk Factors Socioeconomic Factors Surveys and Questionnaires Tobacco Use Urban Population

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