RM-493, a melanocortin-4 receptor (MC4R) agonist, increases resting energy expenditure in obese individuals.

Chen KY, Muniyappa R, Abel BS, Mullins KP, Staker P, Brychta RJ, Zhao X, Ring M, Psota TL, Cone RD, Panaro BL, Gottesdiener KM, Van der Ploeg LH, Reitman ML, Skarulis MC
J Clin Endocrinol Metab. 2015 100 (4): 1639-45

PMID: 25675384 · PMCID: PMC4399297 · DOI:10.1210/jc.2014-4024

MeSH Terms (16)

Adult alpha-MSH Anti-Obesity Agents Combined Modality Therapy Cross-Over Studies Double-Blind Method Energy Metabolism Female Humans Male Middle Aged Obesity Receptor, Melanocortin, Type 4 Rest Weight Reduction Programs Young Adult

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