Vertebrate homeodomain proteins: families of region-specific transcription factors.

Wright CV, Cho KW, Oliver G, De Robertis EM
Trends Biochem Sci. 1989 14 (2): 52-6

PMID: 2565051 · DOI:10.1016/0968-0004(89)90043-1

Vertebrate homeodomain proteins are transcription factors whose genes can be isolated via a conserved DNA-binding domain called the homeobox. We review recent studies suggesting that one function of these genes is the early subdivision of the embryo along the antero-posterior axis into 'fields' of cells with different developmental potential.

MeSH Terms (7)

Amino Acid Sequence Animals Drosophila Genes, Homeobox Molecular Sequence Data Transcription Factors Xenopus

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