G-protein-independent coupling of MC4R to Kir7.1 in hypothalamic neurons.

Ghamari-Langroudi M, Digby GJ, Sebag JA, Millhauser GL, Palomino R, Matthews R, Gillyard T, Panaro BL, Tough IR, Cox HM, Denton JS, Cone RD
Nature. 2015 520 (7545): 94-8

PMID: 25600267 · PMCID: PMC4383680 · DOI:10.1038/nature14051

MeSH Terms (20)

Action Potentials Agouti-Related Protein alpha-MSH Animals Eating Energy Metabolism Female GTP-Binding Protein alpha Subunits, Gs HEK293 Cells Homeostasis Humans Ligands Male Melanocortins Mice Neurons Paraventricular Hypothalamic Nucleus Potassium Channels, Inwardly Rectifying Receptor, Melanocortin, Type 4 Signal Transduction

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