Excess of heme induces tissue factor-dependent activation of coagulation in mice.

Sparkenbaugh EM, Chantrathammachart P, Wang S, Jonas W, Kirchhofer D, Gailani D, Gruber A, Kasthuri R, Key NS, Mackman N, Pawlinski R
Haematologica. 2015 100 (3): 308-14

PMID: 25596265 · PMCID: PMC4349268 · DOI:10.3324/haematol.2014.114728

MeSH Terms (25)

Anemia, Hemolytic Anemia, Sickle Cell Animals Antibodies Blood Coagulation Capillary Permeability Cells, Cultured Factor XI Factor XIIa Female Gene Deletion Gene Expression Heme Hemopexin Humans Injections, Intravenous Leukocytes, Mononuclear Macrophages Male Mice Mice, Inbred C57BL Mice, Transgenic RNA, Small Interfering Swine Thromboplastin

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