Novel 3-nitrotriazole-based amides and carbinols as bifunctional antichagasic agents.

Papadopoulou MV, Bloomer WD, Lepesheva GI, Rosenzweig HS, Kaiser M, Aguilera-Venegas B, Wilkinson SR, Chatelain E, Ioset JR
J Med Chem. 2015 58 (3): 1307-19

PMID: 25580906 · PMCID: PMC4337820 · DOI:10.1021/jm5015742

MeSH Terms (16)

Amides Animals Cell Line Chagas Disease Dose-Response Relationship, Drug Methanol Mice Mice, Inbred BALB C Molecular Structure Parasitic Sensitivity Tests Rats Structure-Activity Relationship Triazoles Trypanocidal Agents Trypanosoma brucei rhodesiense Trypanosoma cruzi

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