Further optimization of the M5 NAM MLPCN probe ML375: tactics and challenges.

Kurata H, Gentry PR, Kokubo M, Cho HP, Bridges TM, Niswender CM, Byers FW, Wood MR, Daniels JS, Conn PJ, Lindsley CW
Bioorg Med Chem Lett. 2015 25 (3): 690-4

PMID: 25542588 · PMCID: PMC4535335 · DOI:10.1016/j.bmcl.2014.11.082

MeSH Terms (12)

Allosteric Regulation Animals Brain Half-Life Humans Imidazoles Indoles Microsomes, Liver Protein Binding Rats Receptor, Muscarinic M5 Structure-Activity Relationship

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