Intrinsic TGF-β2-triggered SDF-1-CXCR4 signaling axis is crucial for drug resistance and a slow-cycling state in bone marrow-disseminated tumor cells.

Nakamura T, Shinriki S, Jono H, Guo J, Ueda M, Hayashi M, Yamashita S, Zijlstra A, Nakayama H, Hiraki A, Shinohara M, Ando Y
Oncotarget. 2015 6 (2): 1008-19

PMID: 25504440 · PMCID: PMC4359213 · DOI:10.18632/oncotarget.2826

MeSH Terms (21)

Animals Antineoplastic Agents Benzylamines Bone Marrow Cell Line, Tumor Chemokine CXCL12 Cisplatin Cyclams Drug Resistance, Neoplasm Gene Expression Regulation, Neoplastic Heterocyclic Compounds Humans Immunoblotting Mice Neoplasms Receptors, CXCR4 Reverse Transcriptase Polymerase Chain Reaction RNA Interference Signal Transduction Transforming Growth Factor beta2 Transplantation, Heterologous

Connections (2)

This publication is referenced by other Labnodes entities:

Links