A novel manganese-dependent ATM-p53 signaling pathway is selectively impaired in patient-based neuroprogenitor and murine striatal models of Huntington's disease.

Tidball AM, Bryan MR, Uhouse MA, Kumar KK, Aboud AA, Feist JE, Ess KC, Neely MD, Aschner M, Bowman AB
Hum Mol Genet. 2015 24 (7): 1929-44

PMID: 25489053 · PMCID: PMC4355025 · DOI:10.1093/hmg/ddu609

MeSH Terms (17)

Amino Acid Motifs Animals Ataxia Telangiectasia Mutated Proteins Cell Line Corpus Striatum Disease Models, Animal DNA Damage Female Humans Huntington Disease Male Manganese Mice Neural Stem Cells Phosphorylation Signal Transduction Tumor Suppressor Protein p53

Connections (4)

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