Methods and challenges in quantitative imaging biomarker development.

Abramson RG, Burton KR, Yu JP, Scalzetti EM, Yankeelov TE, Rosenkrantz AB, Mendiratta-Lala M, Bartholmai BJ, Ganeshan D, Lenchik L, Subramaniam RM
Acad Radiol. 2015 22 (1): 25-32

PMID: 25481515 · PMCID: PMC4258641 · DOI:10.1016/j.acra.2014.09.001

Academic radiology is poised to play an important role in the development and implementation of quantitative imaging (QI) tools. This article, drafted by the Association of University Radiologists Radiology Research Alliance Quantitative Imaging Task Force, reviews current issues in QI biomarker research. We discuss motivations for advancing QI, define key terms, present a framework for QI biomarker research, and outline challenges in QI biomarker development. We conclude by describing where QI research and development is currently taking place and discussing the paramount role of academic radiology in this rapidly evolving field.

Copyright © 2015 AUR. Published by Elsevier Inc. All rights reserved.

MeSH Terms (8)

Animals Biomarkers Humans Image Interpretation, Computer-Assisted Molecular Diagnostic Techniques Molecular Imaging Molecular Probes Molecular Probe Techniques

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