Kinome-wide functional screen identifies role of PLK1 in hormone-independent, ER-positive breast cancer.

Bhola NE, Jansen VM, Bafna S, Giltnane JM, Balko JM, Estrada MV, Meszoely I, Mayer I, Abramson V, Ye F, Sanders M, Dugger TC, Allen EV, Arteaga CL
Cancer Res. 2015 75 (2): 405-14

PMID: 25480943 · PMCID: PMC4297507 · DOI:10.1158/0008-5472.CAN-14-2475

MeSH Terms (23)

Animals Antineoplastic Combined Chemotherapy Protocols bcl-X Protein Breast Neoplasms Cell Cycle Proteins Drug Synergism Estradiol Estrogen Receptor alpha Female Fulvestrant Humans MCF-7 Cells Mice Mice, Nude Neoplasms, Hormone-Dependent Protein-Serine-Threonine Kinases Proto-Oncogene Proteins Pteridines Random Allocation RNA, Small Interfering Transcription, Genetic Transcription Factors Xenograft Model Antitumor Assays

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