Reactive γ-ketoaldehydes promote protein misfolding and preamyloid oligomer formation in rapidly-activated atrial cells.

Sidorova TN, Yermalitskaya LV, Mace LC, Wells KS, Boutaud O, Prinsen JK, Davies SS, Roberts LJ, Dikalov SI, Glabe CG, Amarnath V, Barnett JV, Murray KT
J Mol Cell Cardiol. 2015 79: 295-302

PMID: 25463275 · PMCID: PMC4302000 · DOI:10.1016/j.yjmcc.2014.11.013

MeSH Terms (17)

Aldehydes Amines Amyloid Animals Atrial Natriuretic Factor Cardiac Pacing, Artificial Cell Line Curcumin Cytosol Heart Atria Humans Mice Models, Biological Oxidative Stress Protein Folding Protein Multimerization Superoxides

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