ATF6 activation reduces the secretion and extracellular aggregation of destabilized variants of an amyloidogenic protein.

Chen JJ, Genereux JC, Qu S, Hulleman JD, Shoulders MD, Wiseman RL
Chem Biol. 2014 21 (11): 1564-74

PMID: 25444553 · PMCID: PMC4254654 · DOI:10.1016/j.chembiol.2014.09.009

MeSH Terms (14)

ADP-Ribosylation Factor 6 ADP-Ribosylation Factors Amino Acid Substitution Endoplasmic Reticulum HEK293 Cells Hep G2 Cells Humans Kinetics Prealbumin Protein Stability Recombinant Fusion Proteins Tetrahydrofolate Dehydrogenase Transfection Unfolded Protein Response

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