Anti-microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways.

Gomez IG, MacKenna DA, Johnson BG, Kaimal V, Roach AM, Ren S, Nakagawa N, Xin C, Newitt R, Pandya S, Xia TH, Liu X, Borza DB, Grafals M, Shankland SJ, Himmelfarb J, Portilla D, Liu S, Chau BN, Duffield JS
J Clin Invest. 2015 125 (1): 141-56

PMID: 25415439 · PMCID: PMC4382246 · DOI:10.1172/JCI75852

MeSH Terms (14)

Animals Autoantigens Collagen Type IV Disease Progression Fibrosis Kidney Metabolic Networks and Pathways Mice, 129 Strain MicroRNAs Nephritis, Hereditary Oligoribonucleotides, Antisense Reactive Oxygen Species Transcriptome Up-Regulation

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