MAP2K1 (MEK1) Mutations Define a Distinct Subset of Lung Adenocarcinoma Associated with Smoking.

Arcila ME, Drilon A, Sylvester BE, Lovly CM, Borsu L, Reva B, Kris MG, Solit DB, Ladanyi M
Clin Cancer Res. 2015 21 (8): 1935-43

PMID: 25351745 · PMCID: PMC4401580 · DOI:10.1158/1078-0432.CCR-14-2124

MeSH Terms (23)

Adenocarcinoma Adenocarcinoma of Lung Aged Aged, 80 and over Alleles Cell Line DNA Mutational Analysis Exons Female Gene Frequency Genotype Humans Lung Neoplasms Male MAP Kinase Kinase 1 Middle Aged Models, Molecular Mutation Neoplasm Metastasis Neoplasm Staging Prognosis Protein Conformation Smoking

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