PPARĪ³ activation attenuates opioid consumption and modulates mesolimbic dopamine transmission.

de Guglielmo G, Melis M, De Luca MA, Kallupi M, Li HW, Niswender K, Giordano A, Senzacqua M, Somaini L, Cippitelli A, Gaitanaris G, Demopulos G, Damadzic R, Tapocik J, Heilig M, Ciccocioppo R
Neuropsychopharmacology. 2015 40 (4): 927-37

PMID: 25311134 · PMCID: PMC4330506 · DOI:10.1038/npp.2014.268

MeSH Terms (23)

Anilides Animals Conditioning, Operant Dopamine Dopaminergic Neurons gamma-Aminobutyric Acid Heroin Hypoglycemic Agents Male Mice, Transgenic Morphine Narcotics Nucleus Accumbens Pioglitazone PPAR gamma Prefrontal Cortex Rats Rats, Wistar Self Administration Synaptic Transmission Thiazolidinediones Time Factors Ventral Tegmental Area

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