The signaling phospholipid PIP3 creates a new interaction surface on the nuclear receptor SF-1.

Blind RD, Sablin EP, Kuchenbecker KM, Chiu HJ, Deacon AM, Das D, Fletterick RJ, Ingraham HA
Proc Natl Acad Sci U S A. 2014 111 (42): 15054-9

PMID: 25288771 · PMCID: PMC4210282 · DOI:10.1073/pnas.1416740111

MeSH Terms (25)

Amino Acids Animals Biological Transport Cell Nucleus Chromatography Computer Simulation Crystallography, X-Ray Electrons Humans Ligands Lipids Mice Models, Molecular Molecular Conformation Mutation Mutation, Missense Peptides Phosphatidylinositols Signal Transduction Solvents Steroidogenic Factor 1 Surface Plasmon Resonance Surface Properties Temperature Water

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