Translational research on Barrett's esophagus.

Baruah A, Buttar N, Chandra R, Chen X, Clemons NJ, Compare D, El-Rifai W, Gu J, Houchen CW, Koh SY, Li W, Nardone G, Phillips WA, Sharma A, Singh I, Upton MP, Vega KJ, Wu X
Ann N Y Acad Sci. 2014 1325: 170-86

PMID: 25266024 · DOI:10.1111/nyas.12531

The following, from the 12th OESO World Conference: Cancers of the Esophagus, includes commentaries on translational research on Barrett's esophagus that address evidence for genetic instability in esophageal cancer; the role of microsatellite instability; the use of histologic and serum Doublecortin-like kinase 1 expression for progression of Barrett's esophagus to adenocarcinoma; the oxidative stress in Barrett's tumorigenesis; the genomic alterations in esophageal cancer; in vivo modeling in Barrett's esophagus; epigenetic and transcriptional regulation in Barrett's esophagus and esophageal adenocarcinoma; and normal and disordered regeneration in Barrett's esophagus.

© 2014 New York Academy of Sciences.

MeSH Terms (9)

Animals Barrett Esophagus Biomarkers, Tumor Disease Progression Humans Microsatellite Repeats Oxidative Stress Paris Translational Medical Research

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